PainKillers
- How Safe Are They?
Sales
of over-the-counter (OTC) analgesics are estimated at around $2
billion per year in the US alone.
45
million Americans regularly take painkillers for chronic headaches.
32
million Americans regularly take painkillers for arthritis.
-
You can buy them at your local pharmacist.
-
You can buy them at your local supermarket.
-
You are allowed to self-medicate with them.
So
they Must Be Safe
Mustn't They?
Aleve
(naproxen), an OTC NSAID (non-steroidal anti-inflammatory
drug), is manufactured by Bayer AG (net income 2007: $355.2 million
from sales of $38+ billion). It was introduced in 1976.
On
December 20, 2004, the National Institutes of Health (NIH) announced
research investigators were suspending the use of two drugs naproxen
and Celebrex from its Alzheimers disease prevention trial.
This study was halted after preliminary trial results indicated
that patients taking naproxen were twice as likely to suffer
heart attack or stroke as patients in taking a placebo pill.
These
adverse naproxen effects caused injury to seventy five
of the 2,500 study participants taking this medication. All of
the affected participants experienced these naproxen effects
while taking over-the-counter level doses of naproxen.
Just
days after the naproxen side effects announcement was made,
Pfizer Inc. said its best-selling arthritis drug Celebrex
was associated with increased heart risks,.
An
FDA Health warning now accompanies naproxen. The emphasis
is on not taking the drug for more than 10 days.
A
Boston study reported in 2005 that women who regularly take painkillers
such as acetaminophen/paracetamol and ibuprofen
are twice as likely to develop high blood pressure as women who
don't. This was surprising mostly because until the time of this
report most of the adverse side-effects were linked to NSAIDs.
Acetaminophen/paracetamol was considered safe unless taken
in overdose.
This
was the second-time that acetaminophen/paracetamol had
been implicated in a long-term study. It seems that regular use
of this particular drug triples chances of kidney disease and
accounts for 20% of all cases requiring kidney transplants or
dialysis.
It
is well-known that no long-term studies are ever made on the safety
of drugs. Drugs are big business. Development costs are huge.
$3 billion was earned from one new drug in the second year after
its introduction. Profits have to be made quickly because drug
patents are relatively short-lived and when they expire anyone
can manufacture it. So it is important to establish brand names
on the pharmacy and supermarket shelves.
Spending
on drug advertising has gone from $11 billion in 1997 to nearly
$30 billion in 2005, congressional investigators discovered. Profit
margins among the leading pharmaceutical companies routinely have
been three and four times higher than in other Fortune 500 industries.
Codeine
(metabolises to morphine after ingestion) has long been
thought to be at least free of side-effects. But, since it is
a narcotic, the only real problem with taking it is addiction.
Now, however, a study in Canada has shown that there is a danger
of morphine overdose to breast-fed infants (Codeine
is often used as a painkiller after a Caesarean Section). Several
cases of morphine overdose, and one fatality, in breast-fed infants
have been reported from Canada.
Almost
all painkillers and NSAIDs leach folic acid from the body. This
carries with it risks of birth defects, anaemia and cardiovascular
disease.
Vioxx,
a Cox-2 inhibitor was introduced, along with a sister drug Celebrex,
in 1999. Cox-2 inhibitors are NSAIDs that target the Cox-2 enzyme
responsible for inflammation. This drug was a 'miracle' for arthritis
sufferers when it was introduced. A little over 12 months later
they were generating 100 million prescriptions and earning $3 billion
a year. In 2001 Celebrex alone was earning $3.1 billion.
Vioxx
was the most heavily advertised prescription drug in 2000.
Vioxx
was withdrawn from sale in 2004.
Merck (net income 2007: $5,151.8 million, from sales
of $10+ billion), its manufacturer, was ordered to pay $253.4 million
to the widow of a man who died from a heart attack. The man had
been taking Vioxx.
Merck
is currently facing thousands of law-suits.
Celebrex
is manufactured by Pfizer (net income 2007: $8,144 million from
sales of $48+ billion)
From
the Celebrex web site:
"...CELEBREX may increase the chance of a heart attack or
stroke that can lead to death."
"Serious skin reactions or stomach and intestine problems,
such as bleeding and ulcers, can occur without warning and may cause
death."
Celebrex
is readily available on prescription.
Other
Cox-2 inhibitor drugs have been withdrawn. Those left carry similar
frightening Health Warnings. There is a very real danger of heart
attacks and strokes as a result of taking members of this group
of painkilling drugs.
OTC
painkillers are big business.
Tylenol
is a well-known US pharmaceutical brand. It is an acetaminophen
(US) / paracetamol (Rest of the World) based brand name.
Various products, both liquid and solid, are available with this
branding. Some of these products include other drugs.
In
2004 sales of Tylenol (excluding sales to hospitals, nursing
homes, and Wal-Mart stores) totalled $786.5 million. In 2006 the
division of pharmaceutical giant Johnson & Johnson that markets
Tylenol generated revenue of $2.7 billion.
American
Home Products made $116.6 million just from sales of Advil
(ibuprofen) in that same year.
But
there aren't any alternatives...
...are
there?
So
you are suffering from a chronic pain, and I've just told you that
whatever painkiller you choose is going to have the potential to
have a seriously damaging, possibly even fatal, effect on your health
- but there aren't any alternatives.
Well...
that's what the drug companies would like you to believe. After
all, as you can clearly see, they make billions of dollars from
the continuance of your pain. If there was a cure for pain, and
they couldn't patent it and sell it to you, they'd probably spend
a fortune on advertising so you were brainwashed into believing
that their particular drug was your best-bet for long-term pain-relief.
Thinking about it, that's exactly what they do do. So maybe there
is a cure for pain after all.
Pain
can be relieved without the use of drugs.
Wow!
that's a powerful statement. If I was as wealthy as the drug companies
I'd have no problem re-programming many people's thinking to believe
that. All I'd have to do is come up with a catchy name and flash
images and words during the commercial breaks of favourite tv programs
for a while. Conviction would follow. Especially since you would
intuitively know that the information I gave you made sense at a
deep level within you.
But
I'm not as wealthy as the drug companies so I have to take this
low-key approach.And just so you know I'm not some nut with a web
page trying to trick you into buying something useful, check out
John
Sarno's book (UK)
or John
Sarno's other book
(US) or all
of these
(US) or
even these
(UK).
Now
I know you want something to take away the pain now (I can possibly
do that, but we'll come to that in a minute), you don't want to
wait even as long as a day, never mind three or four, for your book
to arrive from Amazon, and then read all the way through it, and
then practise whatever it suggests and then experience only some
slight relief as you perfect the techniques suggested. Though slight
relief at least suggests more relief to follow.
There
are only two real problems to finding relief from pain.
1.
Sufferers want instant relief (even though they don't get that from
painkillers - even an injection of novocaine takes a few minutes
to reach full potency.)
2.
Sufferers don't want to have to do it themselves.
I have
on many occasions satisfied the instant relief part (click
here to discover more) - well faster than ibuprofen mixed with
codeine.
And
I've done about 70% of the work. So if you are prepared to do that
30% of effort yourself then click here.
If
you don't want my help, or even believe that I can
help you, then I would like to leave you with these thoughts to
ponder.
The
majority of the suffering that comes from pain is the result of
fear.
Remove
the fear and the suffering will be gone - even though the pain may
still remain.
Pain
is an illusion - a very real-seeming, attention grabbing, mind-grabbingly
terrifying, illusion - but nightmares can be all of those things
too, and no one has to work very hard to convince you a nightmare
is an illusion created by your own mind.
Pain
can be relieved or removed by learning to see through the illusion.
Chronic
thoughts are the only reason you experience chronic pain.
If
you want to discover how, in around 40 minutes from now, you could
possibly, just possibly, experience anything from some welcome relief,
to total freedom from, pain then click
here NOW.
And
just so you know, it will cost you some money, but probably not
as much as your next visit to the pharmacist.
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